Article
The genetics of hypogonadotropic hypogonadism.
Seminars in reproductive medicine - 1 Jul 2007
Bhagavath Balasubramanian, Layman Lawrence C
Abstract excerpt
An up-to-date review of the genetic aspects of idiopathic hypogonadotropic hypogonadism (IHH)/Kallmann syndrome (KS) is presented. Because proper development of the neuroendocrine axis must occur for normal puberty and reproductive function, gonadotropin-releasing hormone (GnRH) neuron migration is outlined first, followed by an introduction to the in vitro analysis of GnRH neuron migration. The normal...
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