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Article

The role of Six1 signaling in paclitaxel-dependent apoptosis in MCF-7 cell line

18 Dec 2015

Abstract excerpt

The resistance of cancer cells to chemotherapeutic agents represents the main problem in cancer treatment. Despite intensive research, mechanisms of resistance have not yet been fully elucidated. Six1 signaling has an important role in the expansion of progenitor cell populations during early embryogenesis. Six1 gene overexpression has been strongly associated with aggressiveness, invasiveness, and poor prognosis...

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PMID: 26773176
DOI: 10.17305/bjbms.2016.674

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