Article
A quantitative method for defining high-arched palate using the Tcof1(+/-) mutant mouse as a model.
Developmental biology - 15 Jul 2016
Conley Zachary R, Hague Molly, Kurosaka Hiroshi, Dixon Jill, Dixon Michael J, Trainor Paul A
Abstract excerpt
The palate functions as the roof of the mouth in mammals, separating the oral and nasal cavities. Its complex embryonic development and assembly poses unique susceptibilities to intrinsic and extrinsic disruptions. Such disruptions may cause failure of the developing palatal shelves to fuse along the midline resulting in a cleft. In other cases the palate may fuse at an arch, resulting in a vaulted oral cavity,...
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