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Article

Structural Illumination of Equine MHC Class I Molecules Highlights Unconventional Epitope Presentation Manner That Is Evolved in Equine Leukocyte Antigen Alleles.

Journal of immunology (Baltimore, Md. : 1950) - 15 Feb 2016

Yao Shugang, Liu Jun, Qi Jianxun, Chen Rong, Zhang Nianzhi, Liu Yanjie, Wang Junya, Wu Yanan, Gao George Fu, Xia Chun

Abstract excerpt

MHC class I (MHC I)-restricted virus-specific CTLs are implicated as critical components in the control of this naturally occurring lentivirus and in the protective immune response to the successfully applied attenuated equine infectious anemia virus vaccine in the horse. Nevertheless, the structural basis for how the equine MHC I presents epitope peptides remains unknown. In this study, we investigated the...

Read the complete abstract on PubMed

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Share to Antigen Presentation
Share to Antigens, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epitopes, T-Lymphocyte

Share to Histocompatibility Antigens Class I

Share to Horses

Share to Infectious Anemia Virus, Equine

Share to Lymphocyte Activation

Share to T-Lymphocytes, Cytotoxic

Source

Identifiers

PMID: 26764037
DOI: 10.4049/jimmunol.1501352

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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