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Article

[Effect of VKORC1 and CYP2C9 variants on dosage of oral anticoagulants in Chilean individuals].

Revista medica de Chile - 1 Nov 2015

Benavides Felipe, Grossman Nicole, Poggi Helena, Nieto Elena, Bertrán Antonio, Araos Daniel, Vásquez Marcos, Ibarra Ignaz, Cáceres Felipe, Espinoza Karena, Lagos Marcela, Lagos Marcel, Repetto M Gabriela

Abstract excerpt

BACKGROUND: The dose of oral anticoagulants (OAC) shows great variability among patients. Pharmacogenetic studies have shown that common variants in genes CYP2C9 (*2 and *3) and VKORC1 (-1639G>A) are associated with lower requirements of OAC. AIM: To study the association between average maintenance doses of oral anticoagulant therapy required to maintain a stable INR and CYP2C9 and VKORC1 gene variants in...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26757860
DOI: 10.4067/S0034-98872015001100001

Genes

VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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