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Article

Down regulated lncRNA MEG3 eliminates mycobacteria in macrophages via autophagy

13 Jan 2016

Abstract excerpt

Small non-coding RNA play a major part in host response to bacterial agents. However, the role of long non-coding RNA (lncRNA) in this context remains unknown. LncRNA regulate gene expression by acting e.g. as transcriptional coactivators, RNA decoys or microRNA sponges. They control development, differentiation and cellular processes such as autophagy in disease conditions. Here, we provide an insight into the...

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PMID: 26757825
DOI: 10.1038/srep19416

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