Article
Cadmium-induced apoptosis and phenotypic changes in mouse thymocytes.
Molecular and cellular biochemistry - 1 Jun 2001
Dong S, Shen H M, Ong C N
Abstract excerpt
At present cadmium (Cd)-induced immunotoxicity and the mechanisms involved have not been fully elucidated. The main objective of the present study is to explore the apoptogenic property of Cd in primary cultured mouse thymocytes and its effect on cell surface marker expression and phenotypic changes. Cd-induced thymocyte apoptosis was determined by TdT-mediated dUTP nick end labeling (TUNEL) assay, DNA...
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