Article
A Novel Molecular Strategy for Surveillance of Multidrug Resistant Tuberculosis in High Burden Settings.
PloS one - 1 Jan 2016
Said Halima M, Kushner Nicole, Omar Shaheed V, Dreyer Andries W, Koornhof Hendrik, Erasmus Linda, Gardee Yasmin, Rukasha Ivy, Shashkina Elena, Beylis Natalie, Kaplan Gilla, Fallows Dorothy, Ismail Nazir A
Abstract excerpt
BACKGROUND: In South Africa and other high prevalence countries, transmission is a significant contributor to rising rates of multidrug resistant tuberculosis (MDR-TB). Thus, there is a need to develop an early detection system for transmission clusters suitable for high burden settings. We have evaluated the discriminatory power and clustering concordance of a novel and simple genotyping approach, combining...
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