Article
Cell-Specific Cre Strains For Genetic Manipulation in Salivary Glands.
PloS one - 1 Jan 2016
Maruyama Eri O, Aure Marit H, Xie Xiaoling, Myal Yvonne, Gan Lin, Ovitt Catherine E
Abstract excerpt
The secretory acinar cells of the salivary gland are essential for saliva secretion, but are also the cell type preferentially lost following radiation treatment for head and neck cancer. The source of replacement acinar cells is currently a matter of debate. There is evidence for the presence of adult stem cells located within specific ductal regions of the salivary glands, but our laboratory recently...
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