Spleen enlargement is a risk factor for thrombosis in essential thrombocythemia: Evaluation on 1,297 patients.

doi:10.1002/ajh.24269

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Article

Spleen enlargement is a risk factor for thrombosis in essential thrombocythemia: Evaluation on 1,297 patients.

American journal of hematology - 1 Mar 2016

Andriani Alessandro, Latagliata Roberto, Anaclerico Barbara, Spadea Antonio, Rago Angela, Di Veroli Ambra, Spirito Francesca, Porrini Raffaele, De Muro Marianna, Crescenzi Leonetti Sabrina, Villivà Nicoletta, De Gregoris Cinzia, Montefusco Enrico, Polverelli Nicola, Santoro Cristina, Breccia Massimo, Cimino Giuseppe, Majolino Ignazio, Mazzucconi Maria Gabriella, Vianelli Nicola, Alimena Giuliana, Montanaro Marco, Palandri Francesca

Abstract excerpt

Spleen enlargement, present in 10-20% of Essential Thrombocythemia (ET) patients at diagnosis, is a feature clinically easy to assess, confirmable by echography with a very low chance of misinterpretation. Nonetheless, the clinical and prognostic role of splenomegaly has been seldom evaluated. From 1979 to 2013, 1297 ET patients retrospectively collected in the database of the Lazio Cooperative Group and Bologna...

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PMID: 26748894
DOI: 10.1002/ajh.24269

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