Article
Leukocytosis and risk stratification assessment in essential thrombocythemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 Jun 2008
Carobbio Alessandra, Antonioli Elisabetta, Guglielmelli Paola, Vannucchi Alessandro M, Delaini Federica, Guerini Vittoria, Finazzi Guido, Rambaldi Alessandro, Barbui Tiziano
Abstract excerpt
PURPOSE: Established risk factors for thrombosis in essential thrombocythemia (ET) include age and previous vascular events. We aimed to refine this risk stratification by adding baseline leukocytosis. PATIENTS AND METHODS: We enrolled 657 patients with ET followed for a median of 4.5 years who developed 72 major thrombosis. Cox proportional hazard model was performed to analyze the thrombotic risk and to...
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