Article
Risk factors for arterial and venous thrombosis in WHO-defined essential thrombocythemia: an international study of 891 patients.
Blood - 2 Jun 2011
Carobbio Alessandra, Thiele Juergen, Passamonti Francesco, Rumi Elisa, Ruggeri Marco, Rodeghiero Francesco, Randi Maria Luigia, Bertozzi Irene, Vannucchi Alessandro M, Antonioli Elisabetta, Gisslinger Heinz, Buxhofer-Ausch Veronika, Finazzi Guido, Gangat Naseema, Tefferi Ayalew, Barbui Tiziano
Abstract excerpt
In an international collaborative study, a central histologic review identified 891 patients with essential thrombocythemia, strictly defined by World Health Organization criteria. After a median follow-up of 6.2 years, 109 (12%) patients experienced arterial (n = 79) or venous (n = 37) thrombosis. In multivariable analysis, predictors of arterial thrombosis included age more than 60 years (P = .03; hazard ratio...
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