Article
The role of enterocyte defects in the pathogenesis of congenital diarrheal disorders.
Disease models & mechanisms - 1 Jan 2016
Overeem Arend W, Posovszky Carsten, Rings Edmond H M M, Giepmans Ben N G, van IJzendoorn Sven C D
Abstract excerpt
Congenital diarrheal disorders are rare, often fatal, diseases that are difficult to diagnose (often requiring biopsies) and that manifest in the first few weeks of life as chronic diarrhea and the malabsorption of nutrients. The etiology of congenital diarrheal disorders is diverse, but several are associated with defects in the predominant intestinal epithelial cell type, enterocytes. These particular...
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