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Article

LPS-induced CXCR4-dependent migratory properties and a mesenchymal-like phenotype of colorectal cancer cells.

Cell adhesion & migration - 2 Jan 2017

Liu Wen-Ting, Jing Ying-Ying, Yan Fei, Han Zhi-Peng, Lai Fo-Bao, Zeng Jian-Xing, Yu Guo-Feng, Fan Qing-Min, Li Rong, Zhao Qiu-Dong, Wu Meng-Chao, Wei Li-Xin

Abstract excerpt

Colorectal cancer (CRC) is the most commonly diagnosed cancer worldwide, and over 50% of patients will develop hepatic metastasis during the course of their disease. CXCR4 and its ligand, stromal cell-derived factor 1α (SDF-1α)/chemokine (C-X-C motif) ligand 12 (CXCL12) have been revealed as regulatory molecules involved in the spreading and progression of a variety of tumors. Here we have shown that...

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Share to Chemokine CXCL12
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26745593
DOI: 10.1080/19336918.2015.1134404
PMCID: PMC5308227

Genes

CXCR4
CXCL12

Provenance

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