Article

CCL2 supports colorectal cancer proliferation, invasion and metastasis through activating lncRNA GSTM3TV2/ATF4 signaling

2025-11-26

Abstract excerpt

<title>Abstract</title> <p> <bold>Objective:</bold> Despite extensive research and advances in biological knowledge, therapeutic strategies, and prognostic outcomes, colorectal cancer (CRC) remains a common malignancy around the world. Elucidating molecular determinants promoting CRC progression will help develop novel, available, and effective treatment modalities. In this study, we proposed a novel C-C motif...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e7c528f1-0a6e-5101-b896-078e2dacbbb5
DOI: 10.21203/rs.3.rs-7932268/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

CCL2 supports colorectal cancer proliferation, invasion and metastasis through activating lncRNA GSTM3TV2/ATF4 signalingDOI 10.21203/rs.3.rs-7932268/v1Read

Elevated expression of CXCL3 in colon cancer promotes malignant behaviors of tumor cells in an ERK-dependent mannerSemantic proximity Read

Overexpression of the transcription factor ATF3 with a regulatory molecular signature associates with the pathogenic development of colorectal cancerSemantic proximity Read

BRAF D594A mutation defines a unique biological and immuno-modulatory subgroup associated with functional CD8+ T cell infiltration in colorectal cancer.Semantic proximity Read

CSF3 contributes to the invasive and metastatic phenotypes and associates with poor prognosis in patients with colorectal cancer via NF-κB signaling pathwaySemantic proximity Read

CXCL14 suppresses the progression of colon cancer by regulating tumor epithelial-mesenchymal transition and tumor microenvironmentSemantic proximity Read

Long non-coding RNA colon cancer-associated transcript 2: role and function in human cancersSemantic proximity Read

LncRNA IGFL2-AS1 Promotes the Proliferation, Migration, and Invasion of Colon Cancer Cells and is Associated with Patient PrognosisSemantic proximity Read

The synergistic effect of TGM2 and TGFβ2 on the prognosis of colon cancer patientsSemantic proximity Read

Olfm4 Is Highly Expressed In Liver Cancer Patients And As A Biomarker And Therapeutic Target For Liver CancerSemantic proximity Read

Roles of GFPT2 Expression Levels On the Prognosis and Tumor Microenvironment of Colon CancerSemantic proximity Read

IFITM2 is a prognostic in colorectal cancer and promotes progression by activating PI3K/AKT pathwaySemantic proximity Read

Hypoxia-Induced PTTG3P Contributes to Colorectal Cancer Glycolysis and M2 Phenotype of MacrophageSemantic proximity Read