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Article

Genetic Variation in the ABCB1 Gene May Lead to mRNA Level Chabge: Application to Gastric Cancer Cases.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2015

Mansoori Maryam, Golalipour Masoud, Alizadeh Shahriar, Jahangirerad Ataollah, Khandozi Seyed Reza, Fakharai Habibollah, Shahbazi Majid

Abstract excerpt

BACKGROUND: One of the major mechanisms for drug resistance is associated with altered anticancer drug transport, mediated by the human-adenosine triphosphate binding cassette (ABC) transporter superfamily proteins. The overexpression of adenosine triphosphate binding cassette, sub-family B, member 1 (ABCB1) by multidrug-resistant cancer cells is a serious impediment to chemotherapy. In our study we have studied...

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Share to Antimetabolites, Antineoplastic
Share to ATP Binding Cassette Transporter, Subfamily B

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Drug Resistance, Neoplasm

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Source

Identifiers

PMID: 26745103
DOI: 10.7314/apjcp.2015.16.18.8467

Genes

ABCB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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