Article
Heterozygosity increases microsatellite mutation rate.
Biology letters - 1 Jan 2016
Amos William
Abstract excerpt
Whole genome sequencing of families of Arabidopsis has recently lent strong support to the heterozygote instability (HI) hypothesis that heterozygosity locally increases mutation rate. However, there is an important theoretical difference between the impact on base substitutions, where mutation rate increases in regions surrounding a heterozygous site, and the impact of HI on sequences such as microsatellites,...
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