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A mathematical approach to virus therapy of glioblastomas

7 Jan 2016

Abstract excerpt

BACKGROUND: It is widely believed that the treatment of glioblastomas (GBM) could benefit from oncolytic virus therapy. Clinical research has shown that Vesicular Stomatitis Virus (VSV) has strong oncolytic properties. In addition, mathematical models of virus treatment of tumors have been developed in recent years. Some experiments in vitro and in vivo have been done and shown promising results, but have been...

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PMID: 26738889
DOI: 10.1186/s13062-015-0100-7

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