Article
A simulation model for tumor growth controlled by therapeutic agents.
Anticancer research - 1 Jan 2000
Chiatti L, Gentile F P, Schinaia G, Carpino S, Greco C, Floridi A, Benassi M
Abstract excerpt
Results obtained in a controlled tumor growth depend on the experimental model used, the agent employed (drugs, ionizing radiations, heat), aw well as the administration scheduling and the host environment. Empirical search and treatment optimization are related to a discrete number of agent combinations and fractioning, and system parameters and dependencies are strictly connected to biological assumptions. A...
Topics
- Animals
- Cell Line
- Cisplatin
- Doxorubicin
- Drug Evaluation, Preclinical
- Drug Resistance
- Female
- Lymphoma, Large B-Cell, Diffuse
- Mice
- Models, Biological
- Mutation
- Ovarian Neoplasms
