Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Oncolytic potency and reduced virus tumor-specificity in oncolytic virotherapy. A mathematical modelling approach

21 Sept 2017

Abstract excerpt

In the present paper, we address by means of mathematical modeling the following main question: How can oncolytic virus infection of some normal cells in the vicinity of tumor cells enhance oncolytic virotherapy? We formulate a mathematical model describing the interactions between the oncolytic virus, the tumor cells, the normal cells, and the antitumoral and antiviral immune responses. The model consists of a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CAR-T cell therapy research
Share to Viral Infectious Diseases and Gene Expression in Insects
Share to Virus-based gene therapy research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28934210
DOI: 10.1371/journal.pone.0184347

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Oncolytic potency and reduced virus tumor-specificity in oncolytic virotherapy. A mathematical modelling approachPMID 28934210Read ↗

Fighting Cancer with Mathematics and VirusesSemantic proximity Read ↗

Modelling the spatial dynamics of oncolytic virotherapy in the presence of virus-resistant tumor cellsSemantic proximity Read ↗

Modelling the spatial dynamics of oncolytic virotherapy in the presence of virus-resistant tumour cellsSemantic proximity Read ↗

Bistability in a model of tumor-immune system interactions with an oncolytic viral therapySemantic proximity Read ↗

A delay-differential equation model of HIV related cancer--immune system dynamicsSemantic proximity Read ↗

Delay differential model for tumour–immune dynamics with HIV infection of CD4<sup>+</sup>T-cellsSemantic proximity Read ↗

Impact of delays in cell infection and virus production on HIV-1 dynamicsSemantic proximity Read ↗

Modeling and Analysis of a Virus that Replicates Selectively in Tumor CellsSemantic proximity Read ↗

An agent-based model of avascular tumor growth: Immune response tendency to prevent cancer developmentSemantic proximity Read ↗

A mathematical model with aberrant growth correction in tissue homeostasis and tumor cell growth.Semantic proximity Read ↗

Tumour-Associated Macrophages and Oncolytic Virotherapies: A Mathematical Investigation into a Complex DynamicsSemantic proximity Read ↗

A mathematical approach to virus therapy of glioblastomasSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.