Article
Carcinogenesis of nasopharyngeal carcinoma: an alternate hypothetical mechanism.
Chinese journal of cancer - 6 Jan 2016
Poh Sharon Shuxian, Chua Melvin Lee Kiang, Wee Joseph T S
Abstract excerpt
Current proposed mechanisms implicate both early and latent Epstein-Barr virus (EBV) infection in the carcinogenic cascade, whereas epidemiological studies have always associated nasopharyngeal carcinoma (NPC) with early childhood EBV infection and with chronic ear, nose, and sinus conditions. Moreover, most patients with NPC present with IgA antibody titers to EBV capsid antigen (VCA-IgA), which can precede...
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