Article
Epstein-Barr virus infection and the pathogenesis of nasopharyngeal carcinoma: viral gene expression, tumour cell phenotype, and the role of the lymphoid stroma.
Seminars in cancer biology - 1 Aug 1996
Niedobitek G, Agathanggelou A, Nicholls J M
Abstract excerpt
Nasopharyngeal carcinoma (NPC) is the human tumour showing the most consistent association with Epstein-Barr virus (EBV). The recent detection of EBV in in-situ NPC lesions has shed light on the sequence of events leading to the development of invasive NPC, and will be discussed in the context of what is known about EBV infection in non-neoplastic epithelial cells. The association of EBV with different histotypes...
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