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Article

Limited Unfolded Protein Response and Inflammation in Neuroserpinopathy.

Journal of neuropathology and experimental neurology - 1 Feb 2016

López-González Irene, Pérez-Mediavilla Alberto, Zamarbide Marta, Carmona Margarita, Torrejón Escribano Benjamin, Glatzel Markus, Galliciotti Giovanna, Ferrer Isidre

Abstract excerpt

Familial encephalopathy with neuroserpin inclusion bodies (FENIB) is a rare disease characterized by the deposition of multiple intracytoplasmic neuronal inclusions that contain mutated neuroserpin. Tg-Syracuse (Tg-Syr) mice express Ser49Pro mutated neuroserpin and develop clinical and neuropathological features of human FENIB. We used 8-, 34-, 45- and 80-week-old Tg-Syr mice to characterize neuroinflammation and...

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Identifiers

PMID: 26733586
DOI: 10.1093/jnen/nlv011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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