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Article

Novel Promising Estrogenic Receptor Modulators: Cytotoxic and Estrogenic Activity of Benzanilides and Dithiobenzanilides.

PloS one - 1 Jan 2016

Kucinska Malgorzata, Giron Maria-Dolores, Piotrowska Hanna, Lisiak Natalia, Granig Walter H, Lopez-Jaramillo Francisco-Javier, Salto Rafael, Murias Marek, Erker Thomas

Abstract excerpt

The cytotoxicity of 27 benzanilides and dithiobenzanilides built on a stilbene scaffold and possessing various functional groups in aromatic rings previously described for their spasmolytic properties was assayed on three human cancer cell lines (A549 -lung adenocarcinoma, MCF-7 estrogen dependent breast adenocarcinoma and MDA-MB-231 estrogen independent breast adenocarcinoma) and 2 non-tumorigenic cell lines...

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Identifiers

PMID: 26730945
DOI: 10.1371/journal.pone.0145615
PMCID: PMC4701221

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