Article
Can all heritable biology really be reduced to a single dimension?
Gene - 10 Mar 2016
Babbitt Gregory A, Coppola Erin E, Alawad Mohammed A, Hudson André O
Abstract excerpt
A long-held presupposition in the field of bioinformatics holds that genetic, and now even epigenetic 'information' can be abstracted from the physicochemical details of the macromolecular polymers in which it resides. It is perhaps rather ironic that this basic conjecture originated upon the first observations of DNA structure itself. This static model of DNA led very quickly to the conclusion that only the...
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