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Article

Shade avoidance 6 encodes an Arabidopsis flap endonuclease required for maintenance of genome integrity and development.

Nucleic acids research - 18 Feb 2016

Zhang Yijuan, Wen Chunhong, Liu Songbai, Zheng Li, Shen Binghui, Tao Yi

Abstract excerpt

Flap endonuclease-1 (FEN1) belongs to the Rad2 family of structure-specific nucleases. It is required for several DNA metabolic pathways, including DNA replication and DNA damage repair. Here, we have identified a shade avoidance mutant, sav6, which reduces the mRNA splicing efficiency of SAV6. We have demonstrated that SAV6 is an FEN1 homologue that shows double-flap endonuclease and gap-dependent endonuclease...

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Source

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Identifiers

PMID: 26721386
DOI: 10.1093/nar/gkv1474
PMCID: PMC4756833

Genes

FEN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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