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Article

The Protein Arginine Methylase 5 (PRMT5/SKB1) Gene Is Required for the Maintenance of Root Stem Cells in Response to DNA Damage.

Journal of genetics and genomics = Yi chuan xue bao - 20 Apr 2016

Li Qiuling, Zhao Yan, Yue Minghui, Xue Yongbiao, Bao Shilai

Abstract excerpt

Plant root stem cells and their surrounding microenvironment, namely the stem cell niche, are hypersensitive to DNA damage. However, the molecular mechanisms that help maintain the genome stability of root stem cells remain elusive. Here we show that the root stem cells in the skb1 (Shk1 kinase binding protein 1) mutant undergoes DNA damage-induced cell death, which is enhanced when combined with a lesion of the...

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Source

Identifiers

PMID: 27090604
DOI: 10.1016/j.jgg.2016.02.007

Genes

ATM
ATR
PRMT5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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