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Article

Association Between Younger Age and Targetable Genomic Alterations and Prognosis in Non-Small-Cell Lung Cancer.

JAMA oncology - 1 Mar 2016

Sacher Adrian G, Dahlberg Suzanne E, Heng Jennifer, Mach Stacy, Jänne Pasi A, Oxnard Geoffrey R

Abstract excerpt

IMPORTANCE: Non-small-cell lung cancer (NSCLC) diagnosed in young patients is rare, and the genomics and clinical characteristics of this disease are poorly understood. In contrast, the diagnosis of other cancers at a young age has been demonstrated to define unique disease biology. Herein, we report on the association of young age with targetable genomic alterations and prognosis in a cohort of 2237 patients...

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PMID: 26720421
DOI: 10.1001/jamaoncol.2015.4482
PMCID: PMC4819418

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