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Article

A serpinB1 regulatory mechanism is essential for restricting neutrophil extracellular trap generation.

Journal of immunology (Baltimore, Md. : 1950) - 1 Nov 2012

Farley Kalamo, Stolley J Michael, Zhao Picheng, Cooley Jessica, Remold-O'Donnell Eileen

Abstract excerpt

NETosis (neutrophil extracellular trap [NET] generation), a programmed death pathway initiated in mature neutrophils by pathogens and inflammatory mediators, can be a protective process that sequesters microbes and prevents spread of infection, but it can also be a pathological process that causes inflammation and serious tissue injury. Little is known about the regulatory mechanism. Previously, we demonstrated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23002442
DOI: 10.4049/jimmunol.1201167
PMCID: PMC3964884

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A serpinB1 regulatory mechanism is essential for restricting neutrophil extracellular trap generation.PMID 23002442Read ↗

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NETosis and the Immune System in COVID-19: Mechanisms and Potential TreatmentsSemantic proximity Read ↗

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