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Article

Interleukin-10 does not modulate clopidogrel platelet response in mice.

Journal of thrombosis and haemostasis : JTH - 1 Mar 2016

Yin Q, Tai T, Ji J-Z, Mi Q-Y, Zhang M-R, Huang W-J, Cao C-C, Xie H-G

Abstract excerpt

UNLABELLED: ESSENTIALS: It is unclear whether interleukin-10 (IL-10) could affect clopidogrel metabolism and response. The bioactivation of and response to clopidogrel were determined between mice with or without IL-10. Maximum clopidogrel active metabolite levels were the major driver of platelet response to clopidogrel. IL-10 did not modulate maximum levels of clopidogrel active metabolite and its antiplatelet...

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Identifiers

PMID: 26712119
DOI: 10.1111/jth.13238

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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