Gene expression profiling of skin and blood in hidradenitis suppurativa

Abstract excerpt

Dear Editor, Hidradenitis suppurativa (HS) is characterized by recurrent abscesses, nodules and sinus tract formation and is localized mainly in the body folds. The pathogenesis is poorly understood. Mutations in genes encoding essential compounds of the transmembrane protease γ‐secretase, including NCSTN, PSEN1 and PSENEN, have been identified in familial HS.1 2 These mutations may result in impaired Notch...

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