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Article

A Pan-HIV Strategy for Complete Genome Sequencing.

Journal of clinical microbiology - 1 Apr 2016

Berg Michael G, Yamaguchi Julie, Alessandri-Gradt Elodie, Tell Robert W, Plantier Jean-Christophe, Brennan Catherine A

Abstract excerpt

Molecular surveillance is essential to monitor HIV diversity and track emerging strains. We have developed a universal library preparation method (HIV-SMART [i.e.,switchingmechanismat 5' end ofRNAtranscript]) for next-generation sequencing that harnesses the specificity of HIV-directed priming to enable full genome characterization of all HIV-1 groups (M, N, O, and P) and HIV-2. Broad application of the HIV-SMART...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26699702
DOI: 10.1128/JCM.02479-15
PMCID: PMC4809961

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