Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sensitivity during the forced swim test is a key factor in evaluating the antidepressant effects of abscisic acid in mice.

Behavioural brain research - 1 Mar 2016

Qi Cong-Cong, Shu Yu-Mian, Chen Fang-Han, Ding Yu-Qiang, Zhou Jiang-Ning

Abstract excerpt

Abscisic acid (ABA), a crucial phytohormone, is distributed in the brains of mammals and has been shown to have antidepressant effects in the chronic unpredictable mild stress test. The forced swim test (FST) is another animal model that can be used to assess antidepressant-like behavior in rodents. Here, we report that the antidepressant effects of ABA are associated with sensitivities to the FST in mice. Based...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antidepressive Agents
Share to Depressive Disorder

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Evaluation, Preclinical

Share to Hypothalamus

Share to Mice, Inbred ICR

Share to Random Allocation

Share to Swimming

Share to Synapsins

Source

Identifiers

PMID: 26698394
DOI: 10.1016/j.bbr.2015.12.009

Genes

FST

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sensitivity during the forced swim test is a key factor in evaluating the antidepressant effects of abscisic acid in mice.PMID 26698394Read ↗

Learned Immobility Produces Enduring Impairment of the HPA Axis Reactivity in Mice without Replicating the Broad Spectrum of Depressive-Like Phenotype.Semantic proximity Read ↗

Dentate Gyrus Activin Signaling Mediates the Antidepressant Treatment ResponseSemantic proximity Read ↗

Assessment of Susceptibility of Outbred Albino Rats to the Formation of Depression-Like State of Learned Helplessness.Semantic proximity Read ↗

Identification of multiple genetic loci in the mouse controlling immobility time in the tail suspension and forced swimming tests.Semantic proximity Read ↗

Oroxylum indicum Seed Extract as a Potential Antidepressant in Chronic Stress Mouse Model of DepressionSemantic proximity Read ↗

A chronic treatment with fluoxetine decreases 5-HT(1A) receptors labeling in mice selected as a genetic model of helplessness.Semantic proximity Read ↗

Sex-specific diurnal immobility induced by forced swim test in wild type and clock gene deficient mice.Semantic proximity Read ↗

Genotype- and experience-dependent susceptibility to depressive-like responses in the forced-swimming test.Semantic proximity Read ↗

Platycladus orientalis seed extract as a potential triple reuptake MAO inhibitor rescue depression phenotype through restoring monoamine neurotransmitters.Semantic proximity Read ↗

Depressive behavior induced by social isolation of predisposed female rats.Semantic proximity Read ↗

The effect of intracerebroventricular allopregnanolone on depressive-like behaviors of rats selectively bred for high and low immobility in the forced swim test.Semantic proximity Read ↗

Genetic differences in the tail-suspension test and its relationship to imipramine response among 11 inbred strains of mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.