Article
Role of Canagliflozin on function of CD34+ve endothelial progenitor cells (EPC) in patients with type 2 diabetes.
Cardiovascular diabetology - 13 Feb 2021
Nandula Seshagiri Rao, Kundu Nabanita, Awal Hassan B, Brichacek Beda, Fakhri Mona, Aimalla Nikhila, Elzarki Adrian, Amdur Richard L, Sen Sabyasachi
Abstract excerpt
BACKGROUND: Endothelial progenitor cells (EPCs) has been shown to be dysfunctional in both type 2 diabetes mellitus (T2DM) and chronic kidney disease (CKD) leading to poor regeneration of endothelium and renal perfusion. EPCs have been shown to be a robust cardiovascular disease (CVD) risk indicator. Effect of sodium glucose channel inhibitors (SGLT2i) such as Canagliflozin (CG) on a cellular biomarker such as...
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