Article
Metformin improves circulating endothelial cells and endothelial progenitor cells in type 1 diabetes: MERIT study.
Cardiovascular diabetology - 26 Aug 2016
Ahmed Fahad W, Rider Rachel, Glanville Michael, Narayanan Kilimangalam, Razvi Salman, Weaver Jolanta U
Abstract excerpt
BACKGROUND: Type 1 diabetes is associated with increased cardiovascular disease (CVD). Decreased endothelial progenitor cells (EPCs) number plays a pivotal role in reduced endothelial repair and development of CVD. We aimed to determine if cardioprotective effect of metformin is mediated by increasing circulating endothelial progenitor cells (cEPCs), pro-angiogenic cells (PACs) and decreasing circulating...
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