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Article

Identification of epistatic interactions through genome-wide association studies in sporadic medullary and juvenile papillary thyroid carcinomas.

BMC medical genomics - 21 Dec 2015

Luzón-Toro Berta, Bleda Marta, Navarro Elena, García-Alonso Luz, Ruiz-Ferrer Macarena, Medina Ignacio, Martín-Sánchez Marta, Gonzalez Cristina Y, Fernández Raquel M, Torroglosa Ana, Antiñolo Guillermo, Dopazo Joaquin, Borrego Salud

Abstract excerpt

BACKGROUND: The molecular mechanisms leading to sporadic medullary thyroid carcinoma (sMTC) and juvenile papillary thyroid carcinoma (PTC), two rare tumours of the thyroid gland, remain poorly understood. Genetic studies on thyroid carcinomas have been conducted, although just a few loci have been systematically associated. Given the difficulties to obtain single-loci associations, this work expands its scope to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26690675
DOI: 10.1186/s12920-015-0160-7
PMCID: PMC4685628

Genes

CHFR
DIO1
DMGDH
LOXL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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