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Article

Glycoproteomic studies of IgE from a novel hyper IgE syndrome linked to PGM3 mutation.

Glycoconjugate journal - 1 Jun 2016

Wu Gang, Hitchen Paul G, Panico Maria, North Simon J, Barbouche Mohamed-Ridha, Binet Daniel, Morris Howard R, Dell Anne, Haslam Stuart M

Abstract excerpt

Glycans serve as important regulators of antibody activities and half-lives. IgE is the most heavily glycosylated antibody, but in comparison to other antibodies little is known about its glycan structure function relationships. We therefore describe the site specific IgE glycosylation from a patient with a novel hyper IgE syndrome linked to mutations in PGM3, which is an enzyme involved in synthesizing...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26687240
DOI: 10.1007/s10719-015-9638-y
PMCID: PMC4891365

Genes

PGM3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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