Article
The clinicopathological significance of NAB2-STAT6 gene fusions in 52 cases of intrathoracic solitary fibrous tumors.
Cancer medicine - 1 Feb 2016
Huang Shih-Chiang, Li Chien-Feng, Kao Yu-Chien, Chuang I-Chieh, Tai Hui-Chun, Tsai Jen-Wei, Yu Shih-Chen, Huang Hsuan-Ying, Lan Jui, Yen Shao-Lun, Lin Po-Chun, Chen Tse-Ching
Abstract excerpt
NAB2-STAT6 gene fusion drives STAT6 nuclear expression and is the pathognomonic hallmark of solitary fibrous tumors (SFTs). However, no study has systematically analyzed the clinicopathological features, STAT6 immunoexpression status, or the fusion variants of NAB2-STAT6 in intrathoracic SFTs. Fifty-two intrathoracic SFTs were retrieved to appraise histopathology, assess STAT6 immunoexpression, and determine...
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