Article
Characterization of the 5'-flanking region of the human TP53 gene and its response to the natural compound, Resveratrol.
Journal of biochemistry - 1 Apr 2016
Uchiumi Fumiaki, Shoji Koichiro, Sasaki Yuki, Sasaki Moe, Sasaki Yamato, Oyama Takahiro, Sugisawa Kyoko, Tanuma Sei-ichi
Abstract excerpt
Tumour suppressor p53, which is encoded by theTP53gene, is widely known to play an important role in response to DNA damage and various stresses. It has recently been reported that p53 regulates glucose metabolism and that an increase in p53 protein level is induced after serum deprivation or treatments with a natural compound,trans-Resveratrol (Rsv). In this study, we constructed a Luciferase expression vector,...
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