Article
Resveratrol and its Related Polyphenols Contribute to the Maintenance of Genome Stability.
Scientific reports - 25 Mar 2020
Matsuno Yusuke, Atsumi Yuko, Alauddin Md, Rana Md Masud, Fujimori Haruka, Hyodo Mai, Shimizu Atsuhiro, Ikuta Tomoki, Tani Hiroko, Torigoe Hidetaka, Nakatsu Yoshimichi, Tsuzuki Teruhisa, Komai Michio, Shirakawa Hitoshi, Yoshioka Ken-Ichi
Abstract excerpt
Genomic destabilisation is associated with the induction of mutations, including those in cancer-driver genes, and subsequent clonal evolution of cells with abrogated defence systems. Such mutations are not induced when genome stability is maintained; however, the mechanisms involved in genome stability maintenance remain elusive. Here, resveratrol (and related polyphenols) is shown to enhance genome stability in...
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