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Article

The role of p53-target genes in human cancer.

Critical reviews in oncology/hematology - 1 Jan 2000

Tokino T, Nakamura Y

Abstract excerpt

The tumor suppressor gene p53 is mutated in a large proportion of human cancers. In some cellular conditions like DNA damage, the p53 gene is induced and its gene product is posttranscriptionally activated. p53 works as a transcriptional activator and induces the expression of its downstream targ...

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Share to Cancer-related Molecular Pathways
Share to Epigenetics and DNA Methylation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10714958
DOI: 10.1016/s1040-8428(99)00051-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-10714958-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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