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Article

Identification of the BRAF V600E mutation in gastroenteropancreatic neuroendocrine tumors.

Oncotarget - 26 Jan 2016

Park Charny, Ha Sang Yun, Kim Seung Tae, Kim Hee Cheol, Heo Jin Seok, Park Young Suk, Lauwers Gregory, Lee Jeeyun, Kim Kyoung-Mee

Abstract excerpt

Genomic profiles of gastroenteropancreatic neuroendocrine tumors (GEP-NETs) are still insufficiently understood, and the genetic alterations associated with drug responses have not been studied. Here, we performed whole exome sequencing of 12 GEP-NETs from patients enrolled in a nonrandomized, open-labeled, single-center phase II study for pazopanib, and integrated our results with previously published results on...

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Source

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Identifiers

PMID: 26684240
DOI: 10.18632/oncotarget.6602
PMCID: PMC4826187

Genes

BRAF
CNBD1
APC
BCOR
CTNNB1
EGFR
ERBB3
KRAS
MGA
PTEN
RASA1
SMARCB1
SPEN
VHL

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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