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Tumor Specific Recruitment and Reprogramming of Mesenchymal Stem Cells in Tumorigenesis

17 Dec 2015

Abstract excerpt

Non-neoplastic stromal cells harvested from patient tumors were identified as tumor-derived mesenchymal stem cells (MSCs) by their multipotential capacity to differentiate into adipocytes, osteoblasts, and chondrocytes and by the expression of MSC specific cell surface markers. These procedures yielded also epithelial cancer cells and their counterpart MSC from gastric carcinoma (GSC1) and lung carcinoma (LC2)....

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PMID: 26676563
DOI: 10.1002/stem.2269

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