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Mesenchymal stem/stromal cells: Developmental origin, tumorigenesis and translational cancer therapeutics

12 Nov 2020

Abstract excerpt

While a large and growing body of research has demonstrated that mesenchymal stem/stromal cells (MSCs) play a dual role in tumor growth and inhibition, studies exploring the capability of MSCs to contribute to tumorigenesis are rare. MSCs are key players during tumorigenesis and cancer development, evident in their faculty to increase cancer stem cells (CSCs) population, to generate the precursors of certain...

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PMID: 33190044
DOI: 10.1016/j.tranon.2020.100948

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