Article
ALCHEMIST Trials: A Golden Opportunity to Transform Outcomes in Early-Stage Non-Small Cell Lung Cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Dec 2015
Govindan Ramaswamy, Mandrekar Sumithra J, Gerber David E, Oxnard Geoffrey R, Dahlberg Suzanne E, Chaft Jamie, Malik Shakun, Mooney Margaret, Abrams Jeffrey S, Jänne Pasi A, Gandara David R, Ramalingam Suresh S, Vokes Everett E
Abstract excerpt
The treatment of patients with metastatic non-small cell lung cancer (NSCLC) is slowly evolving from empirical cytotoxic chemotherapy to personalized treatment based on specific molecular alterations. Despite this 10-year evolution, targeted therapies have not been studied adequately in patients with resected NSCLC who have clearly defined actionable mutations. The advent of next-generation sequencing has now...
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