Article
Pharmacogenomics and targeted therapy of cancer: Focusing on non-small cell lung cancer.
European journal of pharmacology - 5 May 2015
Haghgoo Seyyed Mortaza, Allameh Abdolamir, Mortaz Esmaeil, Garssen Johan, Folkerts Gert, Barnes Peter J, Adcock Ian M
Abstract excerpt
Recent studies have been established high degree of genetic diversity in solid organ tumors among individuals and even between individual tumor cells. This intratumor and intertumor genetic diversity results in a heterogeneous tumor with unique characteristics which potentially allows effective drug therapy. The goal of pharmacogenomics is to elucidate the genetic network(s) that underlie drug efficacy and drug...
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