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Article

The prevalence of unique SNPs in the renin-angiotensin system highlights the need for pharmacogenetics in Indigenous Australians.

Clinical and experimental pharmacology & physiology - 1 Feb 2016

Grimson Steven, Cox Amanda J, Pringle Kirsty G, Burns Christine, Lumbers Eugenie R, Blackwell C Caroline, Scott Rodney J

Abstract excerpt

Genetic differences between ethnic populations affect susceptibility to disease and efficacy of drugs. This study examined and compared the prevalence of single nucleotide polymorphisms (SNPs) in genes of the renin-angiotensin system (RAS) in a desert community of Indigenous Australians and in non-Indigenous Australians. The polymorphisms were angiotensinogen, AGT G-217A (rs5049); AGT G+174A (rs4762); Angiotensin...

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Identifiers

PMID: 26667052
DOI: 10.1111/1440-1681.12525

Genes

ACE
AGT
AGTR1
REN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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