Article
Structure and function of neonatal social communication in a genetic mouse model of autism.
Molecular psychiatry - 1 Sept 2016
Takahashi T, Okabe S, Broin P Ó, Nishi A, Ye K, Beckert M V, Izumi T, Machida A, Kang G, Abe S, Pena J L, Golden A, Kikusui T, Hiroi N
Abstract excerpt
A critical step toward understanding autism spectrum disorder (ASD) is to identify both genetic and environmental risk factors. A number of rare copy number variants (CNVs) have emerged as robust genetic risk factors for ASD, but not all CNV carriers exhibit ASD and the severity of ASD symptoms varies among CNV carriers. Although evidence exists that various environmental factors modulate symptomatic severity,...
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