Article
Prediction of Long-Term Benefits of Inhaled Steroids by Phenotypic Markers in Moderate-to-Severe COPD: A Randomized Controlled Trial.
PloS one - 1 Jan 2015
Snoeck-Stroband Jiska B, Lapperre Therese S, Sterk Peter J, Hiemstra Pieter S, Thiadens Henk A, Boezen H Marike, Ten Hacken Nick H T, Kerstjens Huib A M, Postma Dirkje S, Timens Wim, Sont Jacob K
Abstract excerpt
BACKGROUND: The decline in lung function can be reduced by long-term inhaled corticosteroid (ICS) treatment in subsets of patients with chronic obstructive pulmonary disease (COPD). We aimed to identify which clinical, physiological and non-invasive inflammatory characteristics predict the benefits of ICS on lung function decline in COPD. METHODS: Analysis was performed in 50 steroid-naive compliant patients with...
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