Article
Phenotypic predictors of response to oral glucocorticosteroids in severe asthma.
Respiratory medicine - 1 Oct 2013
Kupczyk Maciej, Haque Shushila, Middelveld Roelinde J M, Dahlén Barbro, Dahlén Sven-Erik
Abstract excerpt
BACKGROUND: Systemic glucocorticosteroids are side-effect prone but often necessary for the treatment of severe asthma (SA). Our goal was to assess the usefulness of medical history, physiological variables and biomarkers as predictors of response to oral steroids. METHODS: After 4 weeks of treatment optimization, 84 patients with SA and 62 with mild-to-moderate asthma (MA) underwent a 2 week double-blind...
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